How Do Methodological Limitations Affect Toxicology?
Methodological limitations also play a significant role in quantitative toxicology. The design of experiments, the selection of endpoints, and the choice of statistical models can all introduce biases and errors. For example, many toxicity studies rely on high-dose exposures to observe effects within a reasonable timeframe, but these conditions may not accurately reflect real-world exposures. Additionally, some toxic effects may not be captured if inappropriate endpoints are selected, leading to incomplete assessments.
