quantitative limitations

Why is Variability a Concern?

One major quantitative limitation is the variability in biological responses. This variability arises from differences in species, age, sex, genetic makeup, and health status among test subjects. For instance, a chemical may exhibit different toxic effects in rodents compared to humans, making it challenging to accurately extrapolate animal data to predict human outcomes. Even within a species, individual differences can lead to varying responses to the same chemical exposure.

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