How Do Molecular Chaperones Influence Toxicant-Induced Diseases?
Chronic exposure to toxicants can overwhelm cellular protective mechanisms, leading to diseases. Molecular chaperones are implicated in several toxicant-induced diseases, including neurodegenerative disorders, cancer, and liver diseases. For instance, in neurodegenerative diseases, the accumulation of misfolded proteins is a hallmark, and chaperones play a crucial role in managing this proteinopathy.
