How do neurotoxic substances affect neurotransmitter systems?
Neurotransmitter systems are critical for the proper functioning of the nervous system, and neurotoxic substances can disrupt these systems in several ways. For example, some toxins may alter the synthesis, release, or reuptake of neurotransmitters, while others might affect receptor function or signal transduction. The dopaminergic system is notably susceptible to such changes, where exposure to substances like methamphetamine can lead to increased dopamine release and eventual depletion, contributing to neurodegenerative diseases such as Parkinson's.
