Photosensitizing reactions are primarily of two types: phototoxic and photoallergic. Phototoxic reactions are more common and occur when the drug absorbs UV or visible light, leading to skin damage. This type of reaction is dose-dependent and resembles sunburn. On the other hand, photoallergic reactions are less common and involve an immune response. Here, the drug or its metabolite changes into an allergen when exposed to light, leading to an allergic reaction that may resemble eczema.
