How Do Physicochemical Properties Affect Toxicity?
The toxicity of a substance can be significantly affected by its physicochemical properties. For example, non-polar substances are more likely to accumulate in fatty tissues, potentially leading to long-term toxic effects. Conversely, highly polar substances may be rapidly excreted and thus less likely to accumulate. The reactivity of a chemical, determined by properties like its oxidation state, can also influence its potential to cause cellular damage.
