Temperature significantly influences the toxicity of chemicals. At higher temperatures, the increased kinetic energy can enhance the rate of absorption of toxins through biological membranes. This can lead to higher systemic concentrations of the toxicant, increasing its harmful effects. Additionally, temperature can affect the metabolism of toxicants in the body, altering their toxicity. For example, some enzymes that detoxify chemicals in the liver function more efficiently at certain temperatures, affecting the overall toxic burden.
