The mechanisms by which toxins induce headaches vary:
Hypoxia - Carbon monoxide binds to hemoglobin more effectively than oxygen, reducing oxygen delivery to the brain. Neurotoxicity - Heavy metals disrupt neuronal function, causing oxidative stress and inflammation. CNS Depression - Solvents depress the central nervous system, leading to headaches and other neurological symptoms. Cholinergic Toxicity - Pesticides inhibit acetylcholinesterase, increasing acetylcholine levels and causing headaches.