Toxicants can enter the eye through various routes, such as direct contact, airborne exposure, or systemic absorption. Direct contact with chemicals, such as splashes of cleaning agents or industrial solvents, can cause immediate irritation or damage. Airborne particles, fumes, or gases can also penetrate the eye, leading to symptoms like redness, watering, or even chemical burns. Additionally, some toxicants can be absorbed into the bloodstream and reach the eye via systemic circulation.