How Do Toxicologists Address Drug Resistance in TB?
Drug resistance is a significant hurdle in TB treatment. Toxicologists work on developing new compounds that target resistant strains while maintaining a favorable safety profile. This involves identifying novel targets within the bacterium that are less likely to mutate, as well as exploring combination therapies that can prevent the emergence of resistance. Toxicologists also play a role in optimizing dosing regimens to minimize toxicity while maximizing efficacy.
