What is the Role of Toxicology in TB Drug Development?
Toxicology is essential in evaluating the safety profile of new TB drugs. It involves assessing the potential adverse effects of drug candidates on biological systems. This includes studies on acute, sub-chronic, and chronic toxicity, as well as reproductive and developmental toxicity. By understanding these effects, toxicologists help in optimizing the drug's therapeutic index, ensuring that the benefits outweigh the risks.