Toxins can inhibit or alter the activity of sodium-potassium ATPase by binding to the enzyme or affecting its regulatory pathways. Some well-known inhibitors include cardiac glycosides like digoxin and ouabain, which are used therapeutically to treat heart conditions but can be toxic at high doses. These compounds inhibit the enzyme, leading to increased intracellular sodium levels, which can disrupt cellular homeostasis and trigger toxic effects.
