transport mechanisms

How Do Transport Mechanisms Influence Toxicity?

Transport mechanisms significantly affect how a toxin exerts its effects. The ability of a toxin to cross biological membranes determines its distribution within the body and its potential to reach target organs. For instance, the blood-brain barrier is a selectively permeable barrier that protects the brain from many toxins, but some lipophilic substances can penetrate this barrier easily. Understanding these mechanisms aids in predicting toxicokinetics and the impact of toxins on health.

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