age specific mortality rates

How Does Age Impact the Metabolism of Toxic Substances?

Aging affects the body's ability to metabolize and excrete toxic substances. In older adults, metabolic rates generally decrease, and there may be changes in liver and kidney function, which are critical for detoxification and excretion. These changes can lead to increased accumulation of toxicants, making older adults more susceptible to toxic effects. Conversely, infants and children have immature metabolic pathways, which can also affect how they process toxic substances.

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