The impact of biological synthesis on toxicity can vary. For instance, some compounds become more toxic after metabolic activation, a process known as bioactivation. A classic example is the conversion of the pain reliever acetaminophen into a toxic metabolite that can cause liver damage. Conversely, biological synthesis can also facilitate detoxification by transforming toxins into less harmful substances. Therefore, the role of biological synthesis in toxicokinetics is twofold: it can either attenuate or exacerbate the toxic effects of substances.
