CAR-T cell therapy involves the extraction of T-cells from a patient's blood, which are then genetically modified to express CARs. These CARs are designed to recognize specific antigens present on the surface of cancer cells. Once infused back into the patient, the CAR-T cells can target and destroy cancer cells. This personalized approach has shown significant success in treating hematological malignancies, such as certain types of leukemia and lymphoma.