How Does Dehydration Influence Toxicity in Children and the Elderly?
Children and the elderly are particularly vulnerable to dehydration-induced toxicity. In children, higher surface area to volume ratios increase water loss, making them more susceptible to dehydration. The elderly often have reduced thirst perception and may suffer from chronic illnesses that exacerbate dehydration. This vulnerability can lead to increased toxicity from substances like NSAIDs and other medications.
