The mechanisms of drug-induced toxicity can be complex and multifaceted. Some drugs cause toxicity through direct chemical metabolism, where the drug or its metabolites interact with cellular components, leading to damage. Others might result from an immune-mediated response, where the body's immune system mistakenly attacks its tissues. Additionally, drug interactions can exacerbate toxicity by altering the pharmacokinetics of other medications, leading to increased concentrations and toxicity.