How Does Epigenetics Affect Cancer Susceptibility?
Epigenetic modifications, such as DNA methylation and histone modification, can regulate gene expression without altering the DNA sequence. These changes can influence cancer susceptibility by altering the expression of genes involved in cell growth, apoptosis, and cell cycle control. Environmental exposures can induce epigenetic changes, which may either enhance or mitigate cancer risk. Understanding these modifications is crucial for developing potential interventions.