How Does Genetic Similarity Affect Toxicological Studies?
Genetic similarity can affect the outcomes of toxicological studies in several ways. Similarities in genes related to metabolic pathways can result in similar responses to toxins. For instance, species with similar cytochrome P450 enzymes may metabolize certain chemicals in comparable ways, making them useful models for human toxicity studies. Conversely, genetic differences can lead to variations in susceptibility, necessitating the consideration of genetic diversity in study designs.
