How Does Ingestion of Corrosives Lead to Perforation?
Corrosive ingestion can cause immediate damage to the gastrointestinal mucosa. Strong acids and bases cause coagulative and liquefactive necrosis, respectively. This necrosis can progress to full-thickness damage, leading to perforation. The severity depends on the concentration and volume of the substance ingested, as well as the duration of contact with the mucosa.
