JECFA evaluations are based on a comprehensive review of scientific literature and data submitted by governments, industry, and other stakeholders. The committee examines both human and animal studies, focusing on the identification of potential health hazards. JECFA employs expert toxicologists, chemists, and other specialists to assess the safety and risk levels of substances. Their evaluations involve determining dose-response relationships and identifying no observed adverse effect levels (NOAEL) for various compounds.
