How Does Physiology Affect Toxicological Reactions?
Physiological factors such as body weight, organ function, and overall health can significantly impact an individual's response to toxins. For example, individuals with impaired liver or kidney function may have reduced capacity to metabolize or excrete toxic substances, leading to increased risk of adverse effects. Furthermore, obesity can alter the volume of distribution for lipophilic compounds, affecting their bioaccumulation and toxicity.
