How does regulatory toxicology adapt to new methodologies?
Regulatory toxicology is evolving to incorporate new methodologies that improve safety assessments and streamline the regulatory approval process. Agencies are increasingly embracing approaches like adverse outcome pathways (AOPs), which provide a mechanistic framework for understanding the progression from chemical exposure to adverse health effects. This shift towards mechanism-based evaluation allows for a more efficient assessment of risks and better regulatory decision-making. Moreover, international collaborations are fostering the harmonization of testing guidelines, ensuring that new methodologies are consistently applied across different regulatory frameworks.
