acid base balance

How Does the Body Maintain Acid-Base Balance?


The body maintains acid-base balance through three primary mechanisms: buffer systems, respiratory regulation, and renal regulation. Buffer systems, like bicarbonate, act immediately to resist changes in pH. The respiratory system adjusts pH by manipulating the levels of carbon dioxide (CO2) through changes in breathing rate and depth. The kidneys contribute by excreting hydrogen ions and reabsorbing bicarbonate, although this process takes hours to days to effect change.

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