How does the immune response to Mycobacterium tuberculosis involve toxicity?
The immune response to Mtb involves the activation of macrophages and the release of cytokines, such as TNF-alpha and IFN-gamma. While this response aims to control infection, it can also lead to tissue damage and inflammatory toxicity. Granuloma formation, a hallmark of TB, results from the accumulation of immune cells and can cause significant lung damage over time.
