How Does the Michaelis-Menten Model Apply to Drug Metabolism?
The model is extensively used to study the metabolism of drugs and their biotransformation into active or inactive forms. Enzymes such as cytochrome P450 play a significant role in drug metabolism, and their interaction with substrates can be described using Michaelis-Menten kinetics. This helps in understanding how variations in enzyme activity, due to genetic differences or environmental factors, can affect drug efficacy and toxicity.
