mechanisms of toxicity

How Does Toxicity Manifest at the Organ Level?

Organ-specific toxicity often arises due to the unique metabolic and physiological functions of different organs. For example:
- Hepatotoxicity: The liver is a primary site for detoxification and is vulnerable to damage from metabolites of toxic substances.
- Nephrotoxicity: The kidneys filter blood and can accumulate toxicants, leading to renal damage.
- Neurotoxicity: The nervous system can be affected by chemicals that alter neurotransmission or damage neurons.

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