TSCA has undergone significant amendments to address its shortcomings. The Frank R. Lautenberg Chemical Safety for the 21st Century Act, passed in 2016, represents the most substantial reform. This update mandates the EPA to prioritize and evaluate existing chemicals systematically, increases public transparency, and provides the EPA with stronger authority to require testing and regulate chemicals. These changes aim to enhance the protection of human health and the environment by making the process more science-based and transparent.