Diagnosis of ANS toxicity typically involves a combination of clinical assessment, history taking, and specific laboratory tests to identify the toxin involved. Management strategies vary depending on the toxin but generally include supportive care, removal of the toxin, and specific antidotes where available. For example, the treatment of organophosphate poisoning involves the use of atropine to counteract muscarinic effects and pralidoxime to reactivate acetylcholinesterase.