Detecting chronic inflammation involves a combination of clinical assessment and laboratory tests. Blood markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are commonly used indicators of systemic inflammation. Advanced techniques like biomarker profiling and imaging studies can also help identify and monitor chronic inflammatory conditions. In toxicological studies, specific assays may be employed to measure the presence of inflammatory cytokines and other mediators in response to toxic exposure.