The detection of fibrosis typically involves a combination of histological, biochemical, and imaging techniques. Histological examination remains the gold standard, where tissue samples are stained and analyzed under a microscope to assess the extent of collagen deposition. Biochemical assays can measure levels of collagen and other markers of fibrosis in tissues or bodily fluids. Imaging techniques, such as MRI and ultrasound, offer non-invasive options for assessing fibrosis in organs like the liver and lungs.