How is Nephrotoxicity Managed in Patients Receiving Cisplatin?
Managing nephrotoxicity involves hydration protocols and the use of nephroprotective agents. Patients are often pre-hydrated with intravenous fluids before and after cisplatin administration to promote renal excretion of the drug. Additionally, agents like amifostine may be used to protect renal function. Close monitoring of renal parameters, such as serum creatinine and urine output, is essential to detect early signs of kidney injury.