Implementing refinement in toxicology involves several strategies:
Minimizing Invasiveness: Employing less invasive methods for data collection, such as non-invasive imaging techniques, can significantly reduce animal stress. Improving Housing and Care: Providing enriched environments and appropriate social housing can improve the animals' quality of life. Refining Experimental Procedures: Techniques such as microdosing or the use of in vitro methods can reduce the need for large animal numbers and lower the potential for suffering. Advanced Monitoring: Utilizing modern monitoring technologies to track physiological and behavioral changes can help detect and alleviate distress promptly.
