Examples of refinement in toxicology include the following practices:
Use of Anesthetics and Analgesics: Proper pain management through anesthetics and analgesics during and after procedures to minimize animal suffering. Environmental Enrichment: Providing enrichment items such as toys or nesting material to reduce stress and encourage natural behaviors. Improved Feeding Practices: Offering varied diets that meet the nutritional needs of the animals while also minimizing stress.
