How is the Toxicity of Bioactive Compounds Assessed?
The toxicity of bioactive compounds is assessed through various methods, including in vitro assays, animal studies, and clinical trials. One of the key components of this assessment is determining the LD50, or the dose at which 50% of a test population is expected to die. Additionally, toxicologists also explore the mechanisms of toxicity, such as interaction with cellular receptors, disruption of metabolic pathways, and induction of oxidative stress.
