How is Toxicity Assessed in Psychoactive Substances?
Toxicologists assess the toxicity of psychoactive substances through various methods, including animal studies, in vitro testing, and clinical trials. These assessments focus on determining the lethal dose (LD50), which is the dose required to kill 50% of the test population, and identifying possible side effects. Toxicologists also study the pharmacokinetics and pharmacodynamics of these substances to understand how they are absorbed, distributed, metabolized, and excreted by the body.