Diagnosing vascular damage often involves a combination of clinical evaluation, imaging techniques, and laboratory tests. Blood tests may reveal biomarkers of endothelial dysfunction, oxidative stress, or inflammation. Imaging modalities like ultrasound, CT angiography, or MRI can provide detailed views of the blood vessels to assess structural integrity and detect any abnormalities. Functional tests, such as flow-mediated dilation, can evaluate endothelial function and assess the risk of cardiovascular events.