Extensive research has been conducted to assess the safety of stevioside. Regulatory bodies like the Food and Agriculture Organization (FAO) and the World Health Organization (WHO) have evaluated its safety profile. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an acceptable daily intake (ADI) for stevioside of up to 4 mg/kg body weight. Studies have generally supported its safety, indicating no significant toxic effects at levels within the ADI.
