Several established in vivo tests are used in toxicology to assess different aspects of toxicity:
Acute Toxicity Tests: Determine the adverse effects of a single dose of a substance. These tests help establish the LD50 value, which is the dose lethal to 50% of the test population. Chronic Toxicity Tests: Assess the effects of long-term exposure to a substance, providing insights into its potential to cause chronic health issues. Carcinogenicity Tests: Evaluate whether a substance has the potential to cause cancer, usually conducted over an extended period. Developmental and Reproductive Toxicity Tests: Focus on the effects of a substance on reproduction and development, crucial for understanding risks to unborn children and fertility.
