Several toxins and drugs are known to cause retinal damage. Among them, Chloroquine and Hydroxychloroquine are notable for their potential to induce retinopathy, especially with long-term use. These drugs are commonly used to treat malaria and autoimmune conditions. Tamoxifen, used in breast cancer treatment, can also lead to crystalline retinopathy. Moreover, exposure to Methanol, often found in industrial solvents, can lead to acute retinal damage and permanent vision loss if ingested.