Dissolving microneedles are composed of biodegradable and biocompatible materials that dissolve upon insertion into the skin, releasing their payload in a controlled manner. These microneedles are typically made from polymers such as hyaluronic acid, polyvinylpyrrolidone (PVP), or chitosan, which dissolve completely in the interstitial fluid of the skin. This eliminates the need for removal, reducing the risk of needle breakage and infection.