What are Some Challenges in Using Least Squares in Toxicology?
While the least squares method is powerful, it is not without challenges. One significant issue is the assumption of linearity, which may not always hold true in complex biological systems. Additionally, outliers or data points that deviate significantly from the main trend can skew the results. Toxicologists must carefully assess the appropriateness of the least squares method for their specific data and consider alternative models if necessary.
