What Are Some Common Alternative Assessment Methods?
There are several innovative approaches used in alternative assessment, including:
In vitro testing: These tests use cultured cells or tissues to evaluate the toxic effects of substances. Examples include cell viability assays, genotoxicity tests, and organ-on-a-chip models. In silico methods: Computational models and simulations are used to predict the toxicological properties of chemicals. These methods include quantitative structure-activity relationship (QSAR) models and molecular docking studies. High-throughput screening: Techniques that allow for the rapid testing of a large number of chemicals using automated systems. These methods can quickly identify potential toxicants and prioritize them for further testing. Omics technologies: Genomics, proteomics, and metabolomics can provide comprehensive data on the biological effects of chemicals at the molecular level.
