What are Some Common Toxicological Concerns with Excipients?
Some excipients, despite being generally regarded as safe, can pose toxicological concerns under certain conditions. Issues such as allergic reactions, intolerance, and carcinogenicity have been reported. For instance, lactose, a common filler, can cause digestive issues in lactose-intolerant patients. Propylene glycol, used as a solvent, can cause central nervous system depression in large doses.
