One example is the deletion of genes in the glutathione S-transferase (GST) family, which are critical for detoxification processes. Individuals with deletions in GSTM1 or GSTT1 genes may have an increased risk of adverse effects from environmental toxins like cigarette smoke or industrial pollutants. Another example is the insertion in the CYP2D6 gene, an enzyme involved in drug metabolism. Such insertions can lead to altered metabolic rates, affecting how patients respond to medications.
