What Are Some Limitations of Using Zebrafish Embryos?
While zebrafish embryos are a powerful tool in toxicology, they are not without limitations. One major challenge is the potential for species-specific differences in metabolism and response to chemicals, which may limit the direct extrapolation of results to humans. Additionally, the aquatic environment of zebrafish embryos may not accurately mimic human exposure routes for certain compounds, such as inhalation or dermal contact. Furthermore, some chemicals may not be stable or soluble in water, complicating the testing process.