How Are Zebrafish Embryos Used in Toxicity Testing?
In toxicity testing, zebrafish embryos are exposed to various concentrations of a chemical, and their development is monitored for any abnormalities. Researchers can assess teratogenic effects, which are changes that cause malformations or functional defects in the developing embryo. Endpoints such as mortality, hatching rate, and morphological deformities are commonly evaluated. Advanced imaging techniques allow for detailed observation of sub-lethal effects, such as changes in heart rate and behavior.
