What are the Biological Effects of Malondialdehyde?
MDA is highly cytotoxic and can interact with proteins, DNA, and other cellular components, leading to the formation of adducts that disrupt their normal function. For instance, MDA can form DNA adducts that are mutagenic and potentially carcinogenic. Additionally, MDA-protein adducts can impair enzyme activities and cellular signaling pathways, contributing to cell dysfunction and death.
