Several factors can induce hypertrophy in the context of toxicological exposure:
Chemical Exposure: Certain chemicals can stimulate cell enlargement as a defense mechanism or adaptive response. Drug-Induced Hypertrophy: Medications like phenobarbital can cause liver hypertrophy as they stimulate the production of detoxifying enzymes. Endocrine Disruptors: Compounds that interfere with hormonal systems can lead to organ enlargement, particularly in reproductive organs. Oxidative Stress: Toxicants that induce oxidative stress may cause cells to grow larger to repair damage and maintain function.
